OBAGI Medical Nu-Derm System
A physician-dispensed skincare system that transforms your complexion from the inside out. Developed by dermatologist Dr. Zein Obagi, the Nu-Derm System is a complete, step-by-step regimen clinically designed to address the visible signs of sun damage and aging — revealing brighter, smoother, and healthier-looking skin.
Rather than treating just the surface, Nu-Derm works to correct hyperpigmentation, dark spots, melasma, uneven tone, dullness, fine lines, and rough texture over a consistent course of use. Each product in the system is numbered in the order it's applied, guiding you through a simple morning and evening routine.
What it targets:
Dark spots, hyperpigmentation, and melasma
Uneven skin tone and dull complexion
Fine lines and wrinkles
Rough, uneven texture and sun damage
How the system works: A typical regimen includes a gentle cleanser and toner to prep the skin, brightening treatments to help even tone, an exfoliating step to encourage cell turnover, a hydrating lotion to support the moisture barrier, and daily sunscreen to protect your results. For best results, the system is often paired with a retinoid (such as tretinoin or retinol) and used consistently over roughly 18–24 weeks.
Choose your formulation: Nu-Derm is available in versions tailored to normal/dry and normal/oily skin, in both:
Nu-Derm Rx — prescription-strength system featuring 4% hydroquinone
Nu-Derm Fx — a non-prescription, hydroquinone-free system powered by brightening arbutin
Important: The Nu-Derm Rx System contains prescription-strength hydroquinone and requires a prescription. Because these are professional-grade active ingredients, the system is best used under the guidance of a qualified skincare provider.

